The Vision Behind Painless Skincare
The development of melnee stems from a desire to cater to the “MZ Generation” – a term used in East Asia encompassing Millennials and Gen Z – who lead active, often stressful lives and prioritize self-care. While micro-needle cosmetics have gained recognition for their ability to deliver ingredients that are otherwise difficult to penetrate the skin’s surface⁶, consumer surveys reveal a significant barrier: approximately 73.4% of people hesitate to use them due to concerns about pain or skin irritation. Cosmed Pharmaceutical, a pioneer in needle cosmetics globally⁵, recognized this gap and sought to create a “painless⁴” solution.

Unveiling the “Melting Needles” Technology
The core innovation of melnee lies in its unique “melting needles.” These aren’t just any needles; they are microscopic, crystalized structures made entirely of the beauty ingredient taurine⁷. When applied to the skin, these tiny needles gently penetrate the stratum corneum⁶, then dissolve upon contact with the skin’s natural moisture, releasing encapsulated beauty ingredients. This ensures that the ingredients are absorbed effectively without leaving any residue or causing pain. The brand emphasizes that this technology provides exceptional penetration⁶ and sustained delivery, boosting overall skin performance.

Beyond the innovative delivery system, melnee products are formulated with a rich blend of trending beauty components, specifically chosen to address the diverse concerns of the MZ Generation. A standout ingredient is Rose PDRN³, derived from the “Queen of Roses,” Damask rose. Known for its low molecular weight, excellent penetration, and gentle nature, Rose PDRN is effectively delivered by the melting needles. Other ingredients include Vitamin C derivatives¹⁰, Collagen¹⁶, Niacinamide⁷, and Glutathione⁷, targeting various needs from hydration and texture improvement to brightening and barrier support.

The melnee Product Lineup
The melnee line launches with a vibrant, cherry blossom pink packaging designed to uplift the skincare routine.
Launch Schedule:
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February 2, 2026:
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melnee Positive Skin Mask Dewy White Skin: A brightening mask featuring over 100 million¹⁵ melting needles combined with Vitamin C derivatives¹⁰, Rose PDRN³, and Glutathione⁷ for transparent, smooth skin⁹.

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melnee Positive Skin Mask Rich Moisture: A deeply hydrating mask with over 100 million¹⁵ melting needles, Collagen¹⁶, Rose PDRN³, and Niacinamide⁷ for plump, lustrous skin.

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March 2, 2026:
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melnee Positive Skin Serum: This serum contains over 20 million¹⁵ melting needles, designed to enhance skin texture and deliver rich beauty ingredients for a dewy, plump complexion that prepares the skin for makeup.

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melnee Positive Skin Cream: An intensive care cream with over 13.5 million¹⁵ melting needles to seal in moisture, ensuring long-lasting hydration for a fresh, plump, and dewy finish.

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With this advanced technology, the brand hopes to hear users exclaim, “Japan’s technology, you nailed it!” every morning, reflecting the positive impact on their daily skin performance.
The Future of Skincare from Kyoto
melnee represents a significant leap in the evolution of needle cosmetics, moving beyond the “painful” perception to offer a comfortable and effective solution. By focusing on the needs of the MZ Generation and leveraging cutting-edge research from Cosmed Pharmaceutical, this brand is set to redefine expectations for at-home skincare. This innovation not only elevates daily beauty routines in Japan but also sets a new standard for global beauty trends, making advanced skincare accessible and enjoyable for everyone.
For more information, visit the official melnee brand page and Instagram:
Cosmed Pharmaceutical Co., Ltd. continues its dedication to unique product development from its base in Kyoto, a city where tradition and innovation seamlessly blend. You can learn more about their work on their corporate website.
Note:
¹ Japan’s first micro-needle technology crystallizing taurine into needles, according to TPC Marketing Research Co., Ltd. survey in December 2025.
² Excludes some stores.
³ DNA-Na (moisturizing ingredient).
⁴ Individual results may vary.
⁵ As per “Yakugaku” journal published by The Pharmaceutical Society of Japan.
⁶ Refers to the stratum corneum.
⁷ Moisturizing ingredient.
⁹ Refers to skin impression due to moisture.
¹⁰ 3-O-Ethyl Ascorbic Acid (moisturizing ingredient).
¹⁵ Based on internal company research.
¹⁶ Hydrolyzed Collagen (moisturizing ingredient).*


